Advanced Lipid Panel, Cardio IQ®

Test Code

92145

Alias/See Also

LAB15268

CPT Codes
80061, 83704, 82172, 83695

Includes

Cardio IQ® Cholesterol, Total
Cardio IQ® HDL Cholesterol
Cardio IQ® Triglycerides
Cardio IQ® Non-HDL and Calculated Components
Cardio IQ® Lipoprotein Fractionation, Ion Mobility
Cardio IQ® Apolipoprotein B
Cardio IQ® Lipoprotein (a)

If Triglyceride is >400 mg/dL, then Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).

If Triglyceride is extremely elevated, >1293 mg/dL, this causes interference in the Cardio IQ® Direct LDL assay, therefore this test cannot be added.

Preferred Specimen

3 mL serum AND 1 mL serum

Patient Preparation

If a Cholesterol measurement is to be performed along with Triglycerides, but not part of a Lipid Panel, then the patient should be fasting 9-12 hours prior to collection. If the Cholesterol is ordered as part of a Lipid Panel, then a fasting sample is not required.

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Minimum Volume

1.75 mL AND 0.25 mL

Instructions

Only serum is acceptable

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Moderate to grossly icteric

Methodology
Enzymatic • Spectrophotometric • Ion Mobility • Fixed Rate Nephelometry • Immunoturbidometric • Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Fri; Report available: 4-7 days

Reference Range

See Laboratory Report

Clinical Significance

The advanced lipid profile provides a more comprehensive assessment of dyslipidemia and cardiovascular risk than standard lipid panel measurements.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.