Syphilis VDRL Screen with Reflex to Titer, CSF

Test Code

14268

Alias/See Also

LAB3041073

CPT Codes
86592

Includes

If Syphilis VDRL Screen, CSF is Reactive, then VDRL Titer, CSF will be performed at an additional charge (CPT code(s) 86593).

Preferred Specimen

1 mL CSF collected in a sterile plastic screw-cap vial

Minimum Volume

0.2 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 4 days
Refrigerated: 14 days
Frozen: 60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lipemia

Methodology
Slide Microflocculation

Setup Schedule

Set up: Mon, Wed-Sat; Report available: 1-3 days

Reference Range

Syphilis VDRL Screen, CSF	Non-Reactive
Syphilis VDRL Titer, CSF	<1:1

Clinical Significance

The VDRL test is a nontreponemal (lipoidal antigen) test that can be used to aid in the diagnosis of neurosyphilis using CSF. The diagnosis of neurosyphilis involves a combination of laboratory testing (e.g., CSF cell count, protein, or CSF-VDRL) in the presence of reactive serologic test [nontreponemal (lipoidal antigen) and treponemal] results and neurologic signs and symptoms. Positive VDRL-CSF results (in the absence of blood contamination) are suggestive of neurosyphilis in a person with the appropriate signs and symptoms.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.