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Tobramycin, Trough
Test CodeLAB38
Alias/See Also
Nebcin, Trough; Tobramycin, TroughLevel
CPT Codes
80200
Preferred Specimen
4.5 ml (600 ul min) lithium heparin (green); alternate-SST (gold) or Red (no additive)
Minimum Volume
1 ml (200 ul minimum) plasma; alternate-serum
Instructions
Collect immediately prior to dose. After centrifugation, if not in gel barrier tube, pour off plasma or serum into an aliquot tube
Transport Temperature
Room temp
Specimen Stability
Separated from cells: 4 hours room temp, 7 days refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Icteric: >30 mg/dL bilirubin, Hemolysis: >800 mg/dL hemoglobin, Lipemia: >750 mg/dL; Cephalothin: >500 ug/mL, Lincomycin: >100 ug/mL, Tetracycline: >500 ug/mL, Trimethoprin: >500 ug/mL
Methodology
Turbidimetric Immunoassay
Setup Schedule
Mon- Sun
Reference Range
Trough Ranges: Therapeutic: < 2.0 ug/mL
Toxic: >2.5 ug/mL
Toxic: >2.5 ug/mL
Clinical Significance
Monitoring tobramycin concentrations in serum, along with careful clinical assessment, is the most effective means
of ensuring adequate therapy
of ensuring adequate therapy
Performing Laboratory
Piedmont Athens Regional
