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Testosterone, Total
Test CodeLAB124
CPT Codes
84403
Preferred Specimen
4.5 ml (1.5 ml minimum) SST (gold) or no additive (red top)
Minimum Volume
1.0 ml (500 ul minimum) serum
Other Acceptable Specimens
Gold SST
Instructions
Spin PST or SST and send to lab
Transport Temperature
Room Temperature
Specimen Stability
Separated from cells: 8 hours room temp, 48 hours refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Icteric: >10 mg/dL bilirubin, Hemolysis: >1000 mg/dL hemoglobin, Lipemia: >1800 mg/dL triglycerides
Methodology
Immunoenzymatic
Setup Schedule
Mon- Sun
Reference Range
Serum (ng/dL)
Males 175–781
Females10–75
Males 175–781
Females10–75
Clinical Significance
An abnormally low total testosterone level in males can be indicative of
hypogonadism, hypopituitarism, hyperprolactinemia, renal failure, hepatic cirrhosis, or Kleinfelter's syndrome.
High total testosterone values in males can be caused by adrenal and testicular tumors, congenital adrenal
hyperplasia or abnormalities of the hypothalamic-pituitary-testicular axis. Increased female total testosterone
levels may indicate polycystic ovary syndrome (PCOS), stromal hyperthecosis, ovarian and adrenal tumors,
congenital adrenal hyperplasia and other disorders of the hypothalamic-pituitary-ovarian axis.
hypogonadism, hypopituitarism, hyperprolactinemia, renal failure, hepatic cirrhosis, or Kleinfelter's syndrome.
High total testosterone values in males can be caused by adrenal and testicular tumors, congenital adrenal
hyperplasia or abnormalities of the hypothalamic-pituitary-testicular axis. Increased female total testosterone
levels may indicate polycystic ovary syndrome (PCOS), stromal hyperthecosis, ovarian and adrenal tumors,
congenital adrenal hyperplasia and other disorders of the hypothalamic-pituitary-ovarian axis.
Performing Laboratory
Piedmont Athens Regional
