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Digoxin
MessageSample should be collected 8-12 hours after oral dose. After centrifugation, if not in gel barrier tube, pour off plasma or serum into an aliquot tube.
Test Code
LAB23
Alias/See Also
Lanoxin
CPT Codes
80162
Preferred Specimen
Lithium Heparin (PST)
Minimum Volume
4.5 ml (4.5 ml min) lithium heparin (green); alternate-SST(gold) or Red (no additive)
Other Acceptable Specimens
Gold SST
Instructions
Spin PST or SST and send to lab
Transport Container
1.5 ml (1 ml minimum) plasma; alternate-serum
Transport Temperature
Room temp
Specimen Stability
Separated from cells: 8 hours room temp, 7 days refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Icteric: >30 mg/dL bilirubin, Hemolysis: >800 mg/dL hemoglobin, Lipemia: >1000 mg/dL triglycerides
Methodology
Homogeneous enzyme immunoassay
Setup Schedule
Mon-Sun
Reference Range
Therapeutic: 0.9 – 2.0 ng/mL
Clinical Significance
Monitoring serum digoxin concentrations, along with careful clinical assessment, is the most effective means of ensuring safe
and effective therapy
and effective therapy
Performing Laboratory
Piedmont Athens Regional