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D-dimer
MessageIf the specimen is not immediately sent to the Piedmont Lab within an hour of collection, spin and freeze platelet free plasma. Note citrated plasma on the pour off tube. See instructions.
Test Code
LAB313
Alias/See Also
Dimer
CPT Codes
85379
Preferred Specimen
light blue top (sodium citirate) tube
Minimum Volume
Full tube, no partial fills
Instructions
Centrifuge light blue-top tube 15 minutes at approx. 1500 x g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (< 10,000/mcL). Freeze immediately and sent frozen to Piedmont Lab
Specimen Stability
4 hours room temp (whole blood or spun sample); Plasma: 8hrs room temp, 1month at-20C.
Methodology
Turbidimetric immunoassay
Setup Schedule
Mon-Sun
Limitations
Overfilled or underiflled tube, clotted or hemolyzed, vigourous mixing, patients with HCT >55%.
Reference Range
<500ng/mL FEU
Clinical Significance
The determination of D-Dimer is becoming a widespread
tool for diagnosing thrombosis and monitoring thrombolytic therapy. Elevated levels of D-Dimer are found in clinical conditions such as deep vein thrombosis (DVT, pulmonary
embolism (PE) and disseminated intravascular coagulation (DIC). D-Dimer levels also rise during the normal
pregnancy but very high levels are associated with complications.
tool for diagnosing thrombosis and monitoring thrombolytic therapy. Elevated levels of D-Dimer are found in clinical conditions such as deep vein thrombosis (DVT, pulmonary
embolism (PE) and disseminated intravascular coagulation (DIC). D-Dimer levels also rise during the normal
pregnancy but very high levels are associated with complications.
Performing Laboratory
Piedmont Athens Regional
