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Beta-hydroxybutyriate
Test CodeLAB1946
Alias/See Also
Ketones, Beta-hydroxybutyric acid
CPT Codes
82010
Preferred Specimen
Lithium Heparin (PST)
Minimum Volume
4.5 ml (2.0 ml min) lithium heparin (green); alternate-SST (gold) or Red (no additive) tubes
Other Acceptable Specimens
Gold (SST)
Instructions
Spin and refrigerate within 2 hours after collection
Transport Temperature
Refrigerated
Specimen Stability
1 week refrigerated
Methodology
Quantitative enzymatic
Setup Schedule
Mon- Sun
Limitations
Lactic dehydrogenase and lactate have been shown to interfere with the assay.
Reference Range
0.02-0.27 mmol/L (healthy people after an overnight fast)
Clinical Significance
The detection of ketosis is important in several clinical conditions. The most important is the detection of
potentially fatal ketoacidosis in diabetics. Patients with Type 1 diabetes are prone to developing ketoacidosis—an
excessive buildup of ketones in the blood due to accelerated ketone synthesis and the body’s limited capacity to
break them down.
potentially fatal ketoacidosis in diabetics. Patients with Type 1 diabetes are prone to developing ketoacidosis—an
excessive buildup of ketones in the blood due to accelerated ketone synthesis and the body’s limited capacity to
break them down.
Performing Laboratory
Piedmont Athens Regional
