Cortisol, A.M.

Test Code

4212

CPT Codes
82533

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Collect specimen between 7-9 a.m. Indicate the collection time on the specimen container and test requisition.
Collect 1 mL serum from a red-top (no gel) tube or serum separator tube; place in sterile plastic screw-capped vial(s).

Note: Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Reference Range

0-3 Days (infants)
Premature (31-35 Weeks)	≤15.0 mcg/dL
Term	≤14.0 mcg/dL
4 Days-1 Month	Not established
2-11 Months 8 a.m. (7-9 a.m.) specimen	3.0-23.0 mcg/dL
1-17 Years 8 a.m. (7-9 a.m.) specimen	3.0-25.0 mcg/dL
>17 Years 8 a.m. (7-9 a.m.) specimen	4.0-22.0 mcg/dL

Clinical Significance

Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency).

Performing Laboratory
Quest Diagnostics Nichols Institute Chantilly
14225 Newbrook Dr
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.