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Vitamin E (Tocopherol)
Test Code931
CPT Codes
84446
Includes
Vitamin E, Alpha-Tocopherol and Vitamin E, Beta-Gamma-Tocopherol
Preferred Specimen
2 mL serum protected from light
Patient Preparation
Overnight fasting is required
Minimum Volume
0.7 mL
Instructions
Allow blood to clot at room temperature for 30 minutes. Centrifuge to separate serum from the cells within 24 hours of collection and immediately pour serum into a plastic transport tube.
Transport Container
Amber plastic tube, or foil wrapped plastic screw-cap vial - protected from light
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic sera • Serum unseparated from the clot • Serum in serum separator tube (SST) not separated from the gel • Received room temperature • Not light protected • Plasma
Methodology
Chromatography
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 3-4 days
Reference Range
See Laboratory Report
Clinical Significance
Deficiency of vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153