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Cortisol AM Serum
MessagePerformed in Chemistry
NOTE:
BCGMC sends to BDMC
BGFMC sends to BIMC
OCH sends to NCMC
PCMH, TCH and WMC send to WyMCC
Page and BPMC send to Sonora Quest Laboratories
NOTE:
BCGMC sends to BDMC
BGFMC sends to BIMC
OCH sends to NCMC
PCMH, TCH and WMC send to WyMCC
Page and BPMC send to Sonora Quest Laboratories
Test Code
CORTAM
Alias/See Also
For Page and BPMC, refer to SQL Test Code 8137 for testing requirements - see link below.
CPT Codes
82533
Preferred Specimen
Green LiHep, Plasma
WyMCC, TCH, PCMH, WMC, Page and BPMC - SST
WyMCC, TCH, PCMH, WMC, Page and BPMC - SST
Other Acceptable Specimens
Gold/SST, Red
Instructions
For BUMCT, testing should be drawn between 0600-1000.
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Clinical Significance
Cortisol (hydrocortisone) is quantitatively the major glucocorticoid product of the adrenal cortex. The main reason to measure
cortisol is to diagnose human diseases which are caused by the overproduction of cortisol in Cushing’s syndrome (CS), deficiency of
adrenal steroid excretion in Addison’s disease, and for therapy monitoring (e.g. therapies designed to reduce the excessive
production of cortisol in Cushing's syndrome and hormone replacement therapy in Addison's disease). Cortisol plays an important
role in the regulation of many essential physiological processes, including energy metabolism, maintenance of electrolyte balance
and blood pressure, immunomodulation and stress responses, cell proliferation as well as cognitive functions. The major fraction of
cortisol circulates bound to plasma proteins as corticosteroid binding globulin and albumin. The biologically active free fraction
comprises only 2-5 % of the total hormone concentration.
Elevated serum levels can be found in stress responses, psychiatric diseases, obesity, diabetes, alcoholism and pregnancy, which
may cause diagnostic problems in patients with Cushing's syndrome. Low levels of cortisol are seen in patients with rare adrenal
enzyme defects and after long-lasting stress. For diagnostic purposes the following analyses are used: Total and free cortisol in
serum.
cortisol is to diagnose human diseases which are caused by the overproduction of cortisol in Cushing’s syndrome (CS), deficiency of
adrenal steroid excretion in Addison’s disease, and for therapy monitoring (e.g. therapies designed to reduce the excessive
production of cortisol in Cushing's syndrome and hormone replacement therapy in Addison's disease). Cortisol plays an important
role in the regulation of many essential physiological processes, including energy metabolism, maintenance of electrolyte balance
and blood pressure, immunomodulation and stress responses, cell proliferation as well as cognitive functions. The major fraction of
cortisol circulates bound to plasma proteins as corticosteroid binding globulin and albumin. The biologically active free fraction
comprises only 2-5 % of the total hormone concentration.
Elevated serum levels can be found in stress responses, psychiatric diseases, obesity, diabetes, alcoholism and pregnancy, which
may cause diagnostic problems in patients with Cushing's syndrome. Low levels of cortisol are seen in patients with rare adrenal
enzyme defects and after long-lasting stress. For diagnostic purposes the following analyses are used: Total and free cortisol in
serum.
Additional Information
Cortisol AM Serum
Cortisol, Total, AM - SQL
