A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Osteocalcin, N-MID (OSTEO)
MessagePatient should not be given Biotin within 8 hours of collection.
Test Code
LAB1060
Quest Code
16322
CPT Codes
83937
Preferred Specimen
1 mL serum in gold top tube
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plain red top tube
Instructions
Allow blood to clot at room temperature (20-26° C) and centrifuge immediately to separate the serum from the cells. Freeze as soon as possible.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen 21 days
Refrigerated: 24 hours
Frozen 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Heat inactivated specimens • Specimens stabilized with azide • Patient administered with biotin within 8 hours
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
Setup Schedule
Mon-fri
Report Available
1-4 days
Reference Range
Male (ng/mL) |
Female (ng/mL) |
|
0-4 Years | Not established | Not established |
5-9 Years | 47-142 | 47-142 |
10-13 Years | 49-167 | 49-167 |
14-17 Years | 26-203 | 14-85 |
>17 Years | 9-38 | 8-32 |
Clinical Significance
Osteocalcin, the most abundant non-collagen protein in bone matrix, is a bone-specific, calcium binding protein. Serum osteocalcin levels are related to the rate of bone turnover in various disorders of bone metabolism, e.g., osteoporosis, primary and secondary hyperparathyroidism, and Paget's disease.
Performing Laboratory
Quest Diagnostics Nichols Institute-Chantilly VA |
14225 Newbrook Drive |
Chantilly, VA 20151-2228 |