Streptococcus pneumoniae Antigens, Urine (STPAGU)

Test Code
LAB8195


Quest Code
16786


CPT Codes
87899

Preferred Specimen
3 mL random urine - no preservative


Minimum Volume
0.5 mL


Other Acceptable Specimens
Random urine (boric acid) preserved


Transport Container
Plastic urine container


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 24 hours
Refrigerated: 14 days
Frozen: 14 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Any specimen other than urine


Methodology
Immunochromatography

Setup Schedule
Pm Monday-sunday


Reference Range
Not detected


Clinical Significance
Streptococcus pneumoniae is the leading cause of community- acquired pneumonia and may be the most important agent in community-acquired pneumonia of unknown etiology. Pneumococcal pneumonia has a mortality rate as high as 30%, depending on bacteremia, age and underlying diseases. When not properly diagnosed and treated, S. pneumoniae infection can lead to bacteremia, meningitis, pericarditis, empyema, purpura fulminans, endocarditis and/or arthritis.

Pneumococcal meningitis, a condition that frequently leads to permanent brain damage or death, can occur as a complication of other pneumococcal infection or may arise spontaneously without any preceding illness. It affects persons of all ages, but is most common in children under 5 years, teenagers and young adults, and in the elderly. Progression from mild illness to coma can occur within hours, making immediate diagnosis and antimicrobial treatment critical. Twenty to thirty percent of all pneumococcal meningitis patients will die, often despite several days of appropriate antibiotic treatment.


Performing Laboratory
Quest Diagnostics Nichols Institute-Chantilly VA
14225 Newbrook Drive
Chantilly, VA 20151-2228




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.