Renin Activity, Plasma (RENIN)

Test Code
LAB532


Quest Code
16846


Alias/See Also
RENIN


CPT Codes
84244

Preferred Specimen
1mL plasma collected in EDTA (lavender-top) tube; freeze ASAP


Minimum Volume
0.5 mL


Instructions
After collection sample can be stored at room temperature up to 24 hours. Separate plasma and freeze. Do not refrigerate the sample. Refrigeration will cause cryoactivation to occur and prorenin will convert to renin causing falsely high renin activity result.


Transport Container
Transport tube


Transport Temperature
Frozen


Specimen Stability
Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimen received at room temperature or refrigerated


Methodology
Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Monday-friday


Report Available
5 days


Reference Range
0.25-5.82 ng/mL/h


Clinical Significance
Measurement of the Plasma Renin activity is useful in evaluating hypertension.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.