Cryoglobulin (% Cryocrit), Serum (CRYOG)

LAB713

36562

CRYOG

6 mL serum collected in each of three separate red-top tubes (no gel)

3 mL

Allow serum sample to clot for one (1) hour in a 37° C water bath, oven, incubator, or heat block. After clotting, centrifuge the specimen for 10 minutes at 1600 RCF (G) utilizing one of the 3 options below: 1. In a "warm" centrifuge at 37° C 2. In a bench-top centrifuge placed in a "warm room" at 37° C 3. At room temperature, in a bench-top centrifuge prewarmed by running it for 10 minutes at 1600 RCF (G) After centrifuging, decant serum into a screw-cap vial and transport at room temperature. Note: If the sample is not kept at 37° C during all processing steps, the cryoprecipitate, if present, can precipitate out of solution and be lost in the clot or during the centrifugation process and result in a false negative result. DO NOT REFRIGERATE OR FREEZE. No other tests can be added to the tube; Cryocrit and Cryoglobulin evaluation only.

Transport tube

Room temperature

Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable

Received refrigerated or frozen, SST tube, gross hemolysis or lipemia

Monday-sunday

None detected (if Cryoglobulin is detected, the %Cryocrit will also be reported)

The cryocrit is primarily intended for following a patient with previously defined and quantitated cryoglobulins. The cryocrit may consist of cryoglobulins, fibrins or mixtures of cryoglobulins and fibrins. If not previously characterized, consider ordering Cryoglobulin Screen with Reflex to Cryoglobulin Profile, Serum.