Mitochondrial Antibody w/Reflex to Titer (MITAB)

Test Code
LAB513


Quest Code
259


Alias/See Also
MITAB


CPT Codes
86381

Includes
If Mitochondrial Antibody Screen is positive, then Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86381).


Preferred Specimen
0.5 mL serum in gold top tube


Minimum Volume
0.1 mL


Other Acceptable Specimens
Plain red top tube


Transport Container
Transport tube


Transport Temperature
Refrigerate (room temperature OK)


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic


Methodology
Immunofluorescent Assay (IFA)

Setup Schedule
Set up 7: 00am; Exp rel 5: 00pm Monday, tuesday, wednesday, thursday, and friday


Report Available
3 days


Reference Range
Negative


Clinical Significance
A high Anti-Mitochondrial Antibody (AMA) titer supports the diagnosis of primary biliary cirrhosis (PBC). Low titers of AMA may be detected in other liver disorders, which include chronic active hepatitis and cryptogenic cirrhosis. Mitochondrial M2 Antibody has an even higher specificity for PBC.


Performing Laboratory
Quest Diagnostics - South Region




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.