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Gabapentin, Plasma (GABAP)
Test CodeLAB470
Quest Code
3557
Alias/See Also
GABAP
CPT Codes
80171
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Draw sample 2 hours after last dose
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube or lithium heparin (green-top) tube
Instructions
Draw sample two hours after last dose. Separate serum or plasma from red cells as soon as possible; Pipette or pour into plastic transport tubes.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 12 days
Frozen: 30 days
Refrigerated: 12 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Monday-friday
Report Available
4 days
Reference Range
2.7-4.1: (peak) following a single dose of 900-1800 mg/day.
4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.
The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.
4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.
The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.
Clinical Significance
Gabapentin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.
Performing Laboratory
| Quest Diagnostics Nichols Institute-Chantilly VA |
| 14225 Newbrook Drive |
| Chantilly, VA 20151-2228 |
