Toxoplasma Antibodies (IgG, IgM) (TOXOGM)

Test Code
LAB2416

Quest Code
8636

Alias/See Also
TOXOGM

CPT Codes
86777,86778

Preferred Specimen
1 mL serum in gold top tube

Minimum Volume
0.6 mL

Other Acceptable Specimens
Plain red top tube

Transport Container
Transport tube

Transport Temperature
Refrigerated

Specimen Stability
Room temperature: 4 days

Refrigerated: 7 days

Frozen: 30 days

Methodology
Immunoassay (IA)

Limitations
The U.S. Food and Drug Administration (FDA) is advising physicians that they should not use the result from any one Toxoplasma IgM commercial test kit as the sole determinant of recent Toxoplasma infection when screening a pregnant patient. Because these tests can have false-positive results, reliance on a single test result could lead to misdiagnosis, resulting in unnecessary treatment of the patient and/or termination of the pregnancy.

Reference Range
Toxoplasma Antibody (IgG)
IU/mL Interpretation
<7.20 Negative
7.20-8.79 Equivocal
>8.79 Positive

Toxoplasma Antibody (IgM)
AU/mL Interpretation
<8.00 Negative
8.00-9.99 Equivocal
>9.99 Positive


Clinical Significance
Toxoplasmosis is a parasitic infection caused by the protozoan Toxoplasma gondii. Approximately 23% of the immunocompetent population are asymptomatic carriers of the parasite. The combination of high titers of IgG and IgM antibodies to Toxoplasma gondii is consistent with infection in the last three months. High titers of IgG and low to medium titers of IgM antibodies to Toxoplasma gondii are consistent with infection in the last three to six months.

Performing Laboratory
Quest Diagnostics - South Region




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.