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Fibrin Monomer (FIBMON)
Test CodeLAB1118
Quest Code
11074
Alias/See Also
FIBMON
CPT Codes
85362
Preferred Specimen
1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Platelet poor plasma: Centrifuge light blue-top 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and ship on dry-ice.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 21 days
Refrigerated: Unacceptable
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Hemagglutination (HA)
Setup Schedule
Friday
Reference Range
Negative
Clinical Significance
The Fibrin monomer assay is a qualitative test for the detection of soluble fibrin monomers in plasma. Fibrin monomers are an intermediate product of thrombin proteolysis of fibrinogen. With disseminated intravascular coagulation (DIC) there is an excess of thrombin generation and therefore detectable levels of soluble fibrin monomer. This test may be used in combination with other markers (platelet count, fibrinogen level, D-dimer) and the clinical scenario to determine the presence of DIC.
Performing Laboratory
Quest Diagnostics Nichols Institute-Chantilly VA |
14225 Newbrook Drive |
Chantilly, VA 20151-2228 |