DHEA Sulfate (DHEAS)

Test Code
LAB524


Quest Code
402


Alias/See Also
DHEAS


CPT Codes
82627

Preferred Specimen
1 mL serum in gold top tube


Minimum Volume
0.5 mL


Other Acceptable Specimens
Plain red top tube


Instructions
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.


Transport Container
Serum separator tube (SST)


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Methodology
Immunoassay (IA)

Setup Schedule
8am Mon-fri


Report Available
4 days


Reference Range
Age Male
mcg/dL
Female
mcg/dL
<1 Month ≤282 12-232
1-6 Months ≤50 ≤65
7-11 Months ≤22 ≤22
1-3 Years ≤12 ≤18
4-6 Years ≤22 ≤29
7-9 Years ≤80 ≤81
10-13 Years ≤122 ≤131
14-17 Years 32-303 31-274
Tanner Stages (7-17 Years)  
   Tanner I ≤78 ≤39
   Tanner II ≤71 12-100
   Tanner III 18-111 36-144
   Tanner IV 28-157 36-214
   Tanner V 97-456 39-285
18-21 Years 20-480 44-286
22-30 Years 74-617 14-349
31-40 Years 93-415 19-237
41-50 Years 61-442 15-205
51-60 Years 32-279 5-167
61-70 Years 20-217 9-118
≥70 Years 3-225 4-157


Clinical Significance

DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens.



Performing Laboratory
Quest Diagnostics - South Region




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.