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Intrinsic Factor Blocking Antibody (IFAB)
Test CodeLAB1037
Quest Code
568
Alias/See Also
IFAB
CPT Codes
86340
Preferred Specimen
1 mL serum in gold top tube
Minimum Volume
0.3 mL
Other Acceptable Specimens
Plain red top tube
Instructions
Samples should not be collected from a patient who has received Vitamin B12 injection therapy within the last week
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Tuesday and thursday
Reference Range
Negative
Clinical Significance
Intrinsic Factor, produced by cells lining the stomach, binds Vitamin B12 (cyanocobalamin) to facilitate absorption of the vitamin. Blocking antibody impedes the action of Intrinsic Factor as observed in approximately half of the patients who develop pernicious anemia.
Performing Laboratory
| Quest Diagnostics Nichols Institute-Chantilly VA |
| 14225 Newbrook Drive |
| Chantilly, VA 20151-2228 |
