Tissue Transglutaminase Antibodies (IgG, IgA) (TTABGA)

Test Code
LAB2412


Quest Code
11073


Alias/See Also
TTABGA


CPT Codes
86364 (x2)

Preferred Specimen
1 mL serum in gold top tube


Minimum Volume
0.5 mL


Other Acceptable Specimens
Plain red top tube


Transport Container
Transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic


Methodology
Immunoassay (IA)

Setup Schedule
Noon cutoff in dept; 4pm setup; Report by 11pm Monday thru friday


Report Available
3 days


Reference Range
Tissue Transglutaminase Antibody, IgG
<15.0 U/mL Antibody not detected
≥15.0 U/mL Antibody detected

Tissue Transglutaminase Antibody, IgA
<15.0 U/mL Antibody not detected
≥15.0 U/mL Antibody detected


Clinical Significance
Tissue Transglutaminase Antibody, IgA, is useful in diagnosing gluten-sensitive enteropathies, such as Celiac Sprue Disease, and an associated skin condition, dermatitis herpetiformis. The IgG test is useful in patients who are IgA-deficient. The IgG test also provides support for gluten-sensitive enteropathies beyond the IgA test.


Performing Laboratory
Quest Diagnostics - South Region




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.