Amino Acid Screen, Urine (AAAU)

Test Code

LAB562

Quest Code

36183

CPT Codes
82139, 82570

Includes

Includes: 1-Methylhistidine, 3-Methylhistidine, Alanine, Alpha-Amino Adipic Acid, Alpha-Amino Butyric Acid, Arginine, Asparagine, Aspartic Acid, Beta Alanine, Beta-Amino Isobutyric Acid, Citrulline, Cystathionine, Cystine, Ethanolamine, Gamma-Amino Butyric Acid, Glutamic Acid, Glutamine, Glycine, Histidine, Homocystine, Hydroxylysine, Hydroxyproline, Isoleucine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Sarcosine, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine, Creatinine, Random Urine

Preferred Specimen

2 mL random urine - no preservative

Minimum Volume

0.5 mL

Instructions

Do not use preservatives. Urine with a pH <2.0 will be rejected. Patient age is required for correct interpretation. Provide patient age (required for correct reference range), sex, a brief clinical history, tentative diagnosis, and the therapy over the last three days (drugs, X-ray, infant formula, diet).

Transport Container

Clear top urine collection tube

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Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • pH <2.0

Methodology
Liquid Chromatography/Mass Spectrometry (LC/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

A. M. Mon, wed, fri

Report Available

9 days

Reference Range

See Laboratory Report

Clinical Significance

Amino acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, phenylketonuria, tyrosinemia, citrullinemia, non-ketotic hyperglycinemia, maple syrup urine disease, and homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.