Alpha-Fetoprotein, Tumor Marker (AFPTM)

Test Code
LAB559

Quest Code
237

Alias/See Also
AFPTM

CPT Codes
82105

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Transport Container
Gold top or Plain red top

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 45 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly lipemic

Methodology
Immunoassay (IA)

Setup Schedule
8am Mon, tues, wed, thur, fri

Report Available
4 days

Limitations
Patients who have received monoclonal mouse antibodies may have abnormal results. For any patient taking a high dose of biotin, the specimen should be drawn at least eight hours after the last dose.

Reference Range
                                                 Males(ng/mL)    Females(ng/mL)
0-1 month:                                0.5 - 16387.0    0.5 - 18964.0
1-11 months:                             0.5 - 28.3          0.5 - 77.0
1-3 years:                                  0.5 - 7.9             0.5 - 11.1
4 years or greater:                     <6.1                     <6.1
Pediatric range is based on full term neonates, values for premature infants may be higher. Ranges adopted from: SJ Soldin, et al. "Pediatric Reference Ranges." Third ed. AACC press (1999). This test was performed using the Siemens (DPC) chemiluminescent method. Values obtained from different assay methods cannot be used inter- changeably. AFP levels, regardless of value, should not be interpreted as absolute evidence of the presence or absence of disease.

Clinical Significance

Elevation of serum AFP above values found in healthy individuals occurs in several malignant diseases, most notably nonseminomatous testicular cancer and primary hepatocellular carcinoma. AFP is not recommended as a screening procedure to detect cancer in the general population.



Performing Laboratory
Quest Diagnostics - South Region




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.