Nortriptyline (Aventyl) (NRTL)

Message
Collect specimen >12 hours after last dose.

Test Code
LAB807

Quest Code
272

Alias/See Also
NRTL

CPT Codes
80335 (HCPCS: G0480)

Preferred Specimen
3 mL serum collected in a red-top tube (no gel)

Patient Preparation
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.

Minimum Volume
1.5 mL

Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube

Instructions
Do not use gel barrier tubes. Separate from cells as soon as possible after clotting.

Transport Container
Transport tube

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum Separator Tube (SST®)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Monday-friday

Report Available
4 days

Reference Range
50-150 mcg/L

Clinical Significance
Nortriptyline is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.

Performing Laboratory
Quest Diagnostics Nichols Institute-Chantilly VA
14225 Newbrook Drive
Chantilly , VA 20151-2228




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.