A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Histone Antibodies (HISABY)
Test CodeLAB2524
Quest Code
37056
CPT Codes
83516
Preferred Specimen
1 mL serum in gold top tube
Patient Preparation
Overnight fasting preferred
Minimum Volume
0.3 mL
Other Acceptable Specimens
Plain red top tube
Instructions
Overnight fasting preferred.
Transport Container
Transport tube
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 8 HOURS
Refrigerated: 7 DAYS
Frozen: 30 DAYS
Refrigerated: 7 DAYS
Frozen: 30 DAYS
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received at room temperature
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
Monday, Wednesday, and Friday
Reference Range
Value | Explanation of Results |
<1.0 | Negative |
1.0-1.5 | Weak Positive |
1.6-2.5 | Moderate Positive |
>2.5 | Strong Positive |
Clinical Significance
Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
Performing Laboratory
Quest Diagnostics Nichols Institute-Chantilly VA |
14225 Newbrook Drive |
Chantilly, VA 20151-2228 |