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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Parietal Cell Antibody, ELISA
Message| Interfaced |
Test Code
APCA
Quest Code
15114
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Received room temperature
Methodology
Immunoassay (IA)
Setup Schedule
Tues, thurs
Report Available
4-7 days
Reference Range
| ≤20.0 U | Negative | |
| 20.1-24.9 U | Equivocal | |
| ≥25.0 U | Positive | |
Clinical Significance
Gastric Parietal Cell Antibodies are found in 90% of patients with pernicious anemia. They are also found in autoimmune chronic atrophic gastritis preceding pernicious anemia. The antigenic target is the H+/K+ ATPase gastric proton pump responsible for parietal cell acid generation in the stomach.
Performing Laboratory
| Quest Diagnostics Nichols Institute-Chantilly VA |
| 14225 Newbrook Drive |
| Chantilly, VA 20151-2228 |
