Tick-borne Disease, Acute Molecular Panel

Message

Interfaced

Test Code

TKPNL

Quest Code

94322

Includes

⁠⁠⁠⁠⁠⁠⁠Anaplasma Phagocytophilum DNA, Qualitative Real-Time PCR
Babesia microti DNA, Real-Time PCR
Borrelia miyamotoi DNA, Real-Time PCR,
Ehrlichia chaffeensis DNA, Real-Time PCR
Borrelia Species DNA, Qualitative Real-Time PCR

Preferred Specimen

3 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

1.5 mL

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lithium heparin (green-top) tube • Sodium heparin (green-top) tube

Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range

See Laboratory Report

Clinical Significance

Persons infected with Borrelia miyamotoi most likely have fever, joint pains, fatigue, and headache, though unlike Lyme disease, rash is uncommon.
The diagnosis of Borrelia miyamotoi is most often made by history and clinical examination combined with exposure in endemic areas. Amplification of B. miyamotoi genomic DNA from blood, fluids or tissues confirms the diagnosis.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.