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RHD Red Cell Genotyping

Message
RHD gene encodes the RhD protien, which expresses the D antigen. Rh antigens are immunogenic and antigen incompatibility can lead to hemolytic transfusion reactions and hemolytic disease of the fetus and newborn (HDFN). Serological tests used for Rh pheotyping cannot differentiate between normal or altered epitipes, espcially in variant expression.


Test Code
VRHD


Alias/See Also
Cerner: RHD Red Cell Genotyping


Preferred Specimen
1-2 Lavender tubes (5-10mL)


Minimum Volume
2mL Lavender tube


Report Available
​Vitalant Send Out via EPCH Blood Bank 7 business days


Clinical Significance
RHD gene exhibits significant diversity, with hundreds of allelic variants. Variants can result in weak D or partial D phenotypes which may complicate serologic Rh typing and critical for blood transfusion compatibility.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.