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Histamine, 24-Hour Urine
Test Code4946
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
4 mL urine from a 24-hour urine containing 10 mL 6N HCL collected in a leak-proof container
Patient Preparation
24 Hour Urine Container
Minimum Volume
2 mL
Other Acceptable Specimens
Non-preservative 24-hour urine collected in a leak-proof container
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 14 days
Refrigerated: 14 days
Frozen: 14 days
Methodology
Immunoassay (IA)
FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
A.M. Sets up 2 days a week.
Reference Range
0.006-0.131 mg/24 h
Clinical Significance
Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.
