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Liver Fibrosis, Hepatic Function Panel with Fibrosis-4 (FIB-4) Index
Test Code30710
Includes
Hepatic Function Panel: Total Protein, Albumin, Globulin, Albumin/Globulin Ratio, Total Bilirubin, Direct Bilirubin, Indirect Bilirubin, Alkaline Phosphatase, Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT)
Platelet Count
FIB 4 Index
Platelet Count
FIB 4 Index
Preferred Specimen
Red Top
AND
Lavender Top
AND
Lavender Top
Minimum Volume
0.5 mL in BOTH
Other Acceptable Specimens
Whole blood from a full EDTA (tan-top) tube
Instructions
Note: If drawn with lead testing, EDTA (tan-top) is required
Transport Temperature
Serum: Refrigerated (cold packs)
Whole blood: Room temperature
Whole blood: Room temperature
Specimen Stability
Serum
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: Unacceptable
Whole blood
Room temperature: 48 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: Unacceptable
Whole blood
Room temperature: 48 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
See individual tests
Methodology
Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Reference Range
See Laboratory Report
Clinical Significance
The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4).
