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Procainamide (743X)
Test Code851N
Includes
Procainamide, N-acetylprocainamide, and Procainamide, Total
Preferred Specimen
Red Top

Patient Preparation
Collect as a trough just prior to next dose
Minimum Volume
0.2 mL


Other Acceptable Specimens
Green Top
OR
Lavender Top
OR
Lavender Top
Instructions
Do not use gel barrier tubes
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: Not Established
Refrigerated: 7 days
Frozen: Not Established
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Immunoassay (IA)
Setup Schedule
Sets up 7 days a week.
Reference Range
See Laboratory Report
Clinical Significance
Procainamide is used to treat a variety of atrial and ventricular arrhythmias. Metabolism of procainamide produces an active metabolite N-Acetylprocainamide (NAPA). The concentration of both procainamide and NAPA levels are monitored to assure adequate therapeutic levels of procainamide are achieved and to avoid toxicity.

