Tick-borne Disease, Acute Molecular Panel, Non-Lyme

Test Code

32338

Includes

Anaplasma Phagocytophilum DNA, Qualitative Real-Time PCR
Babesia microti DNA, Real-Time PCR
Borrelia miyamotoi DNA, Real-Time PCR, Miscellaneous
Ehrlichia chaffeensis DNA, Real-Time PCR

Preferred Specimen

Lavender Top

Minimum Volume

1.5 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen -20° C: 30 days
Frozen -70° C: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Heparin as an anticoagulant

Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

See individual assays

Reference Range

Anaplasma phagocytophilum DNA, QL Real Time PCR	Not Detected
Babesia microti DNA, Real-Time PCR	Not Detected
Borrelia miyamotoi DNA, Real-Time PCR, Misc	Not Detected
Ehrlichia chaffeensis DNA, Real-Time PCR	Not Detected

Clinical Significance

Persons infected with Borrelia miyamotoi most likely have fever, joint pains, fatigue, and headache, though unlike Lyme disease, rash is uncommon.
The diagnosis of Borrelia miyamotoi is most often made by history and clinical examination combined with exposure in endemic areas. Amplification of B. miyamotoi genomic DNA from blood, fluids or tissues confirms the diagnosis.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.