Androstenedione, Response to ACTH Stimulation

Test Code

19511

Includes

Androstenedione, Baseline
Androstenedione, 60 Minutes

Preferred Specimen

Red Top

Minimum Volume

0.25 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), EDTA (royal blue-top), sodium heparin (green-top), or lithium heparin (green-top) tube

Instructions

Serum separator tubes are unacceptable. Draw blood in a red-top tube (no gel). Separate serum after clotting. Do not submit glass tubes.
An early morning specimen is preferred. Draw baseline specimen. Draw another specimen 60 minutes after stimulation.

Note: Cortrosyn (cosyntropin) not supplied by the laboratory.
This test cannot be collected at a Patient Service Center.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 2 years

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Samples collected in serum separator tubes (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

A.M. Sets up 6 days a week.

Reference Range

See Laboratory Report

Clinical Significance

Androstenedione may be useful in evaluating patients with androgen excess and managing patients with congenital adrenal hyperplasia (CAH),

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.