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Acetonitrile Exposure Profile, Blood
Test Code35385
Includes
Acetaldehyde, Acetone, Cyanide
Preferred Specimen
Gray Top

Minimum Volume
1.1 mL
Instructions
Collect sample using alcohol free skin preparation.
Studies have shown that cyanide has variable instability in biological specimens and is particularly unstable in some postmortem specimens. The loss of cyanide can be minimized shipping the sample to the laboratory for analysis as soon as possible, preferably using refrigerated or frozen transportation and preservation using sodium fluoride/potassium oxalate (gray-top) tube. Samples should not be refrozen if previously thawed. The potential for increases in cyanide concentrations, although rare, have also been demonstrated and may be due to microbial action. Preservation with sodium fluoride may reduce this possibility.
Transport Container
Sodium fluoride/potassium oxalate (gray-top) tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: Undetermined
Refrigerated: Not stable
Frozen: Undetermined
Refrigerated: Not stable
Frozen: Undetermined
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received refrigerated
Methodology
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) • Headspace Gas Chromatography (GC)
Reference Range
See Laboratory Report

