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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Histone Antibodies
Test Code37056 (80944)
Preferred Specimen
Red Top
Patient Preparation
Overnight fasting preferred
Minimum Volume
0.3 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 24 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
A.M. Sets up 3 days a week.
Report Available
Reports in 2 to 5 days.
Reference Range
| Value | Explanation of Results |
| <1.0 | Negative |
| 1.0-1.5 | Weak Positive |
| 1.6-2.5 | Moderate Positive |
| >2.5 | Strong Positive |
Clinical Significance
Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
