Cytochrome b5 Reductase Enzyme Activity, Blood

Test Code

39856

Preferred Specimen

6 mL Lavender Top

Minimum Volume

1 mL

Other Acceptable Specimens

N/A

Instructions

Send specimen in original tube. Do not transfer blood to other containers. Patient's age is required.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 18 days
Frozen: Unacceptable

Methodology
Kinetic Spectrophotometry

FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule

Setup: Performed Weekly; varies, Reports: 1 Day

Reference Range

≥12 months

7.8-13.1 U/g Hb

Reference values have not been established for patients who are <12 months of age.

Clinical Significance

Evaluation of patients with cyanosis.
Confirming cases of suspected cytochrome b5 reductase (methemoglobin reductase) deficiency.
Functional studies in families with cytochrome b5 reductase deficiency.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.