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Delta Aminolevulinic Acid, Random Urine
Test Code6301 (8406)
Preferred Specimen
Urine collected in Sterile Cup
PROTECT FROM LIGHT
PROTECT FROM LIGHT
Minimum Volume
0.6 mL
Other Acceptable Specimens
Urine preserved with 1 mL concentrated glacial acetic acid or 1 mL 6N HCl, protected from light, catherized urine in sterile, plastic, screw-capped container
Instructions
Wrap container in alumuninum foil to protect from light. Do not use preservatives.
Do not use first morning void, late evening specimen (after 8 p.m.), or specimen after excessive fluid intake. Keep refrigerated and transport refrigerated (cold packs).
Do not use first morning void, late evening specimen (after 8 p.m.), or specimen after excessive fluid intake. Keep refrigerated and transport refrigerated (cold packs).
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not protected from light
Methodology
Colorimetric (C)
Setup Schedule
P.M.
Reference Range
| 1-8 Years | 2.3-6.2 mg/g creat |
| 9-17 Years | 1.5-5.3 mg/g creat |
| ≥18 Years Male | <1.8 mg/g creat |
| ≥18 Years Female | <5.4 mg/g creat |
Clinical Significance
ALA is a precursor to uroporphyrin, coproporphyrin, and protoporphyrin. Concentrations of ALA are greatly increased in many patients with acute neurological forms of porphyrias and in some patients with chronic alcohol abuse.
