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IgG Synthesis Rate/Index, CSF
Test Code7558 (8009)
Alias/See Also
Cerner : IgG Index/csf
Includes
Albumin (CSF and Serum)
IgG (CSF and Serum)
IgG Index, CSF
Synthesis Rate IgG, CSF
IgG (CSF and Serum)
IgG Index, CSF
Synthesis Rate IgG, CSF
Preferred Specimen
2 mL CSF in a sterile screw cap container and 1 mL serum
Minimum Volume
1 mL CSF and 0.5 mL serum
Instructions
Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 90 days
Refrigerated: 7 days
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Received room temperature • Xanthochromia • RBCs • Hemolysis in CSF
Methodology
Nephelometry
Setup Schedule
Night; A.M. Sets up 5 days a week.
Reference Range
See Laboratory Report
Clinical Significance
The IgG Synthesis Rate/Index is useful in diagnosing and monitoring patients with multiple sclerosis and other inflammatory diseases involving the brain and meninges.

