Syphilis Antibody Cascading Reflex (Reverse Algorithm)

Test Code
90349


CPT Codes
86780

Includes
If T. pallidum Antibody is equivocal or positive, then RPR Screen with Reflex to Titer will be performed at an additional charge (CPT code(s): 86592).
If RPR Screen is reactive, then RPR titer will be performed at an additional charge (CPT code(s): 86593).
If RPR screen is non-reactive, then T. pallidum Antibody, Particle Agglutination will be performed at an additional charge (CPT code(s): 86780).


Preferred Specimen
3 mL serum


Minimum Volume
1.4 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Daily; Report available: 1-4 days


Reference Range

See Laboratory Report



Clinical Significance
This test is used to aid in the diagnosis of syphilis using the reverse algorithm. The algorithm starts with the Treponema pallidum Antibody immunoassay, a treponemal serologic test. If positive, samples will be further tested using RPR, a nontreponemal (lipoidal antigen) serologic test, and if reactive will reflex to titer. T. Pallidum positive samples that do not confirm with RPR will be tested by a second treponemal test, Treponema Pallidum Particle Aggluctination (TP-PA).




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.