Progesterone Receptor (PR), IHC with Interpretation [36159X]

Test Code
36159


CPT Codes
88360

Preferred Specimen
Formalin-fixed, paraffin embedded tissue submitted in an IHC specimen transport kit


Other Acceptable Specimens
3 unstained, (+) positively charged slides


Instructions
Please include surgical pathology report.

Per ASCO/CAP guidelines, ER (Estrogen Receptor) and PR (Progesterone Receptor) positivity requires at least 1% of tumor cells to show positive nuclear staining of any intensity. A negative result for ER and PR will be reported if < 1% of tumor cells show staining.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemical Assay

Setup Schedule
Set up: Mon-Fri; Report available: 2 days


Reference Range
Interpretive report


Clinical Significance
The presence of progesterone receptors in tumor tissue cells is used to select drug therapy, especially in women with breast carcinoma.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.