Enterovirus/Parechovirus RNA, Qualitative Real-Time PCR

Test Code

70189

CPT Codes
87498, 87798

Preferred Specimen

0.7 mL serum or
0.7 mL CSF collected in a sterile, plastic leak-proof container or
0.7 mL plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.3 mL serum, CSF, plasma • 0.5 gram stool • 1 swab

Other Acceptable Specimens

1 gram stool • Throat or rectal swab collected in an M4 or VCM medium (green-cap or equivalent (UTM))

Transport Temperature

Serum, CSF, plasma: Refrigerated (cold packs)
Stool: Frozen

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Specimens containing heparin • Calcium alginate swabs

Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 2-3 days

Reference Range

Enterovirus RNA, QL PCR	Not detected
Parechovirus RNA, QL PCR	Not detected

Clinical Significance

This broad-spectrum assay detects the genomic RNA of members of the Enterovirus genus (including enteroviruses, echoviruses, coxsackieviruses and polioviruses) as well as the genomic RNA of members of the Parechovirus genus. The use of this assay allows for rapid patient testing as an aid in the diagnosis of viral meningitis or sepsis-like syndromes.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.