|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Chromosome Analysis, Mosaicism, POC Tissue
Test Code39937
CPT Codes
88230, 88263<br>Limited Access Code
Preferred Specimen
5x5 mm fetal tissue collected in a sterile container in Hanks' Ringer's solution or culture medium with antibiotics
Minimum Volume
2x3 mm fetal tissue
Other Acceptable Specimens
5x5 mm fetal tissue in saline solution submitted in a sterile leak-proof container • Cultured cells collected in two T-25 flasks
Instructions
Signed informed consent is a requirement. POC transport media and handling instructions available upon request.
Fetal tissue sample minimum of 2x3 mm collected in a sterile container with Hanks', Ringer's solution, culture medium with antibiotics, or saline solution.
Transport media should be refrigerated before use, but can be shipped at room temperature.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Preferred
Refrigerated: Acceptable
Frozen: Unacceptable
Refrigerated: Acceptable
Frozen: Unacceptable
Methodology
Microscopy • Karyotype • Tissue Culture
Setup Schedule
Set up: Daily; Report available: 15 days
Reference Range
Interpretive report
Clinical Significance
Autosomal or Sex Chromosome Mosaicism not detected in lymphocytes may be determined in fibroblasts obtained from a tissue biopsy. Cells from organ biopsies obtained postmortem may still be suitable for chromosome analysis when the patient's blood is of questionable viability. Fetal tissues or extra embryonic membranes are frequently used to diagnose fetal chromosome abnormalities that are associated with approximately one-half of all first trimester spontaneous abortions.
