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Extended Myositis Specific Antibody (MSA) Panel
Test Code10257
CPT Codes
84182 (x6), 86235 (x5), 83520, 83516
Includes
Myositis Specific 11 Antibodies Panel (Jo-1, PL-7, PL-12, EJ, OJ, SRP, MI-2 alpha and beta, MDA5, TIF1, NXP-2)
3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) Antibody (IgG)
Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody (IgG)
3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) Antibody (IgG)
Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody (IgG)
Preferred Specimen
1.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.9 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 14 days
Refrigerated: 14 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Moderate to gross hemolysis • Received room temperature • Serum separator tube (SST)
Methodology
Chemiluminescence (CL) • Enzyme Linked Immunosorbent Immunoassay (ELISA) • Line Blot
Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 3-6 days
Reference Range
See individual tests
Clinical Significance
The Extended Myositis Specific Antibody (MSA) panel is designed as an aid for the diagnosis of myopathies associated with autoantibody production. These include inflammatory myopathies (polymyositis, anti-synthetase syndrome, dermatomyositis), necrotizing myopathies, including statin associated myopathy, and inclusion body myositis.
