|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Immunoglobulin Kappa Free Light Chain, Spinal Fluid
Test Code18408
CPT Codes
83521<br>Restricted Client Code
Preferred Specimen
1 mL CSF collected in a sterile vial
Minimum Volume
0.5 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 28 days
Refrigerated: 72 hours
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Nephelometry
Setup Schedule
Set up: Mon-Fri; Report available: 1-3 days
Reference Range
Medical Decision Point: 0.1000 mg/dL
Positive: ≥ 0.1000 mg/dL
Borderline: 0.0600 mg/dL-0.0999 mg/dL
Negative <0.0600 mg/dL
Positive: ≥ 0.1000 mg/dL
Borderline: 0.0600 mg/dL-0.0999 mg/dL
Negative <0.0600 mg/dL
Clinical Significance
Diagnosing multiple sclerosis and other demyelinating conditions.
Evaluating patients who present with a clinically isolated syndrome in which the patient reports symptoms (headaches, optic neuritis, fatigue, and many others, depending on the disease location) characteristic of inflammation and demyelination of the central nervous system.
Recommended in cases where the imaging findings are atypical and in populations in which multiple sclerosis is less common (eg, children, older individuals, or non-White populations).
The test is not useful when a clear diagnosis is already known because a positive result does not correlate with severity of the disease or diseases outcomes.
Evaluating patients who present with a clinically isolated syndrome in which the patient reports symptoms (headaches, optic neuritis, fatigue, and many others, depending on the disease location) characteristic of inflammation and demyelination of the central nervous system.
Recommended in cases where the imaging findings are atypical and in populations in which multiple sclerosis is less common (eg, children, older individuals, or non-White populations).
The test is not useful when a clear diagnosis is already known because a positive result does not correlate with severity of the disease or diseases outcomes.
