Barbiturates, Confirmation, Meconium

Test Code

40864

CPT Codes
80345

Includes

Amobarbital, Butabarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital

Preferred Specimen

5 grams of random meconium submitted in plastic leak-proof container

Minimum Volume

1 gram

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Reference Range

See Laboratory Report

Clinical Significance

Extensively used for hypnotics, sedatives, and anesthetics. Readily absorbed from stomach. Duration of action of Barbiturates in therapeutic doses varies from: 8-16 hours (long acting e.g., phenobarbital); 4-8 hours (intermediate acting e.g., Amobarbital); 3-6 hours (short acting e.g., Pentobarbital). Barbiturates may enhance other CNS depressants, such as Ethanol, Morphine derivatives, tranquilizers, and Resperine.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.