Preeclampsia Risk Assessment (sFlt-1/PlGF Ratio)

Test Code

15370

CPT Codes
83520 (x2)<br>Limited Access Code

Preferred Specimen

2 mL serum

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in a K2 EDTA (pink-top) tube

Instructions

Allow serum to clot completely at room temperature. Transfer 2 mL serum or plasma (Min: 0.5 mL) to a standard transport tube.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs) or Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 1 month
Frozen: 1 month

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly hemolyzed, lipemic, and/or icteric specimens

Methodology
Quantitative Immunoassay

Setup Schedule

Set up: Daily; Report available: 2-4 days

Reference Range

≤ 39 ratio

Clinical Significance

This test is to be used in conjunction with other laboratory tests and clinical assessments to aid in the risk assessment of pregnant women (singleton pregnancies between gestational age 23+0 to 34+6/7 weeks) hospitalized for hypertensive disorders of pregnancy (preeclampsia, chronic hypertension with or without superimposed preeclampsia, or gestational hypertension) for progression to preeclampsia with severe features (as defined by American College of Obstetricians and Gynecologists guidelines) within 2 weeks of being tested.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.