Plasma Renin Activity with Reflex to Aldosterone

Test Code

13817

CPT Codes
84244

Includes

If Plasma Renin Activity result is <1.00 ng/mL/h, then Aldosterone will be performed at an additional charge (CPT code(s): 82088).

Preferred Specimen

1.8 mL frozen plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.8 mL

Instructions

Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.

Transport Temperature

Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Moderate to gross hemolysis • Received thawed • Plasma collected in a plasma separator tube (PST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Sun-Fri; Report available: 4-6 days

Reference Range

See Laboratory Report

Clinical Significance

The Aldosterone-renin ratio is used to screen for primary aldosteronism.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.