Peripheral Blood Smear Review

Test Code
13808


CPT Codes
85008

Preferred Specimen
2 glass microscope slide-peripheral smears submitted in slide holder and client provided (in-house) CBC results


Minimum Volume
1 slide • 1 mL whole blood


Other Acceptable Specimens
4.5 mL whole blood collected in an EDTA (lavender-top) tube and client provided(in-house) CBC results


Instructions
This test cannot be collected at a Patient Service Center.

Make slide immediately. Submit slides with CBC results and clinical history.
Note: Test will be cancelled if CBC results are not provided.


Transport Temperature
Room temperature


Specimen Stability

Slide
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable

Whole blood
Room temperature: 48 hours
Refrigerated: 48 hours
Frozen: Unacceptable



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Clotted • No CBC results and clinical history


Methodology
Microscopic Examination

Setup Schedule
Set up: Mon-Fri; Report available: 3-5 days


Reference Range
Not established


Clinical Significance
To supplement client-performed CBC testing with verification of abnormal results and assessment of morphology to aid in the diagnosis of hematological disorders.

Intended for moderate complexity or waived testing sites that require additional review for instrumentation flagging.

Client must supply in-office CBC test results and either 2 glass slides or Lavender EDTA tube. If no client-performed CBC results are received, test will be cancelled.

The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.

Reference
1. Beckman AK, Ng VL, Jaye DL, et al. Clinician-ordered peripheral blood smears have low reimbursement and variable clinical value: a three-institution study, with suggestions for operational efficiency. Diagn Pathol. 2020;15(1):112. doi:10.1186/s13000-020-01033-8
2. Kurt-Mangold ME, Grieme CV, Krasowski MD, Rosenthal NS. Clinical Utility of Ordered Pathology Blood Smear Reviews - an Overused Resource? Clin Lab. 2018;64(1):99-104. doi:10.7754/Clin.Lab.2017.170703
3. Radke, T. Improving utilization of pathologist reviewed blood films. Today's Clinical Lab. (2024-03-05). Accessed Aug. 8, 2024. https://www.clinicallab.com/improving-utilization-of-pathologist-reviewed-blood-films-27782.







The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.