Monoclonal Protein Study, Quantitative, Serum

Test Code

13743

CPT Codes
0077U, 82784 (x3)

Includes

If a light chain is identified without a corresponding heavy chain during initial testing, IFXED (immunofixation with immunoglobulin D [IgD] and immunoglobulin E [IgE] antisera), will be performed at an additional charge (CPT code(s): 86334, 82784, 82785).

If a monoclonal IgD or IgE is identified during initial testing, IGD or IGE will be performed at an additional charge (CPT code(s): 82784 or 82785).

Preferred Specimen

2 mL serum

Minimum Volume

1.5 mL

Instructions

Centrifuge and aliquot serum into 2 plastic vials, each containing 1 mL.

Transport Container

Plastic vials (x2)

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 7 days
Refrigerated: 28 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly lipemic

Methodology
Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) • Nephelometry

FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule

Set up: Mon-Fri; Report available: 2-4 days

Reference Range

See Laboratory Report

Clinical Significance

Aiding in the diagnosis and monitoring of monoclonal gammopathies, when used in conjunction with free light chain studies.

This test alone is not considered an adequate screen for monoclonal gammopathies.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.