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PrEP RPR (Diagnosis) with Reflex Titer and Treponema pallidum Antibody, IA
Test Code13698
CPT Codes
86592
Includes
If RPR screen is Reactive, then RPR Titer and Treponema pallidum Antibody, IA for Confirmatory testing will be performed at an additional charge (CPT Code(s): 86593, 86780).
Preferred Specimen
3 mL serum
Minimum Volume
1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia
Methodology
Flocculation
Setup Schedule
Set up: Mon, Wed- Sat; Report available: 1-3 days
Reference Range
| PrEP RPR(DX) w/Rfl Titer and Confirm Test | Non-Reactive |
| PrEP RPR Titer | Not applicable |
| PrEP Treponema pallidum Ab | Negative |
Clinical Significance
RPR is a nontreponemal (lipoidal antigen) test used to screen for syphilis. Positive RPR samples are reflexed to determine titer and to a confirmatory treponemal assay as part of the traditional algorithm. False positive results associated with various medical conditions, including other infections (e.g., HIV), autoimmune conditions, vaccinations, injecting drug use, pregnancy, and older age may occur with the RPR test.
This assay may be performed as part of an overall screening regimen for patients considering or who are currently taking HIV PrEP. Please refer to the "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States - 2021 Update Clinical Practice Guideline" for additional information.
This assay may be performed as part of an overall screening regimen for patients considering or who are currently taking HIV PrEP. Please refer to the "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States - 2021 Update Clinical Practice Guideline" for additional information.
